The actress joins the Fox medical drama for a guest-starring stint, beginning Mon., Nov. 8. Her character -- a brilliant med student named Martha Masters -- is hired by Cuddy to replace the MIA Thirteen (Olivia Wilde is taking a break from the show to film the movie 'Cowboys and Aliens'), and House is not happy about it. At all.
House's testerone-heavy team give the bright-eyed, bushy-tailed newbie a good hazing, calling her "the Internet with breasts," "the love child of Einstein and Mary Poppins" and "Pippy Long Division" among other nicknames.
Watch what the cast has to say about Tamblyn's debut in our exclusive sneak peek.
Are you excited to watch Amber Tamblyn on 'House'?Sneak Peek - Amber Tamblyn w 'Housie'